Revenue multiples, specialty adjustments, PE acquisition context, and the payor mix factors that move your number most — updated for 2026.
Most medical practices sell for 40%–80% of trailing annual revenue in private-buyer transactions, or 2.5x–5.0x SDE (Seller's Discretionary Earnings). Private equity-backed physician management organizations (PMOs) and hospital systems pay more — often 4x–8x EBITDA — when a practice fits their network strategy.
But these ranges are wide because specialty type, payor mix, associate physician count, and ancillary revenue streams move the number substantially. A cash-pay dermatology practice with two associate physicians and an in-house procedure suite is a fundamentally different asset than a solo Medicaid-heavy primary care practice — even if both report the same top-line revenue.
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Specialty type is the single largest driver of medical practice valuation multiples. The table below reflects 2026 private-buyer transaction ranges. PE acquisition multiples run higher across all specialties.
| Specialty | Revenue Multiple | SDE / EBITDA Multiple | PE Interest |
|---|---|---|---|
| Dermatology | 0.7x – 1.2x | 4.0x – 8.0x | Very High |
| Ophthalmology / Eye Care | 0.6x – 1.1x | 3.5x – 7.0x | High |
| Orthopedics | 0.5x – 1.0x | 3.5x – 7.0x | High |
| Gastroenterology | 0.5x – 1.0x | 3.5x – 6.5x | High |
| Pain Management | 0.5x – 1.0x | 3.0x – 6.0x | High |
| General Practice (this guide's baseline) | 0.4x – 0.8x | 2.5x – 5.0x | Moderate |
| Primary Care / Internal Medicine | 0.4x – 0.8x | 2.5x – 4.5x | Growing |
| Urgent Care | 0.4x – 0.9x | 2.5x – 5.0x | Moderate |
| OB/GYN | 0.4x – 0.8x | 2.5x – 4.5x | Moderate |
| Psychiatry / Behavioral Health | 0.4x – 0.8x | 2.5x – 4.0x | Growing |
| Medicaid-Heavy / FQHC-Style | 0.2x – 0.5x | 1.5x – 3.0x | Low |
Nothing affects medical practice value more than who pays the bills. The hierarchy, from highest to lowest value:
A practice with 40%+ Medicaid revenue will typically trade at the low end of multiples — sometimes below them. A practice with 30%+ cash-pay or out-of-network revenue will trade at the high end.
A solo physician practice is highly exposed to key-person risk. If you are the practice, buyers price that heavily. Every associate physician on staff reduces this risk and adds transferable revenue capacity. Practices with 2+ associate physicians command materially higher multiples than solo practices, all else equal.
In-house ancillary services — imaging, lab, minor surgical procedures, infusion, physical therapy, optical — generate revenue at margins far above professional services. They also represent recurring revenue tied to the facility rather than a specific physician. Ancillary revenue is often the difference between a mid-range and top-range multiple.
ACO participation, capitated managed care contracts, and PCMH designations add strategic value to primary care practices, particularly as hospital systems and PE-backed platforms look to build value-based care networks. A primary care practice with a strong quality track record in value-based care arrangements is a more attractive acquisition target than one billing purely fee-for-service.
PE-backed PMOs have been active acquirers across specialties for the past decade. Their evaluation criteria differ from a private physician buyer's in important ways:
Whether you're talking to a hospital system, a PE group, or a private buyer — walk in with a credible independent valuation.
Get My Medical Practice Valuation →Medical practice valuations use three methods, with results triangulated into a final range:
Apply the specialty-appropriate multiple to trailing 12-month collections (not billings — collections is the number that matters). For a primary care practice collecting $1.4M annually at a 0.6x multiple: $840,000 enterprise value.
Start with net income. Add back: physician owner compensation (all forms), depreciation, amortization, one-time expenses, and any personal expenses run through the practice. The result is SDE — what the practice generates for its owner. Apply the specialty multiple. For the same practice with $350,000 SDE at 3.5x: $1,225,000.
Medical equipment, leasehold improvements, supplies, and accounts receivable minus liabilities. For most practices this produces the lowest value and is used only as a floor, not a primary method.
| Item | Amount |
|---|---|
| Annual collections | $1,500,000 |
| Physician owner compensation (salary + benefits) | $280,000 |
| All other expenses | $870,000 |
| Net income | $350,000 |
| + Add back physician compensation | $280,000 |
| SDE | $630,000 |
| Revenue multiple (0.6x) | $900,000 |
| SDE multiple (3.0x) | $1,890,000 |
| Triangulated value (weighted blend) | ~$1,200,000 – $1,500,000 |
The range reflects the meaningful difference between how buyers weigh revenue vs. earnings-based methods for this practice type. A solo physician practice would land at the lower end; one with an associate MD would justify the higher end.
Multiple ranges in this guide reflect these datasets and industry benchmark surveys as synthesized by the ValueAI Pro valuation engine. Every generated report discloses its full methodology, formulas, and adjustments in an appendix.