Revenue multiples, specialty adjustments, PE acquisition context, and the payor mix factors that move your number most — updated for 2026.
Most medical practices sell for 40%–80% of trailing annual revenue in private-buyer transactions, or 2.5x–5.0x SDE (Seller's Discretionary Earnings). Private equity-backed physician management organizations (PMOs) and hospital systems pay more — often 4x–8x EBITDA — when a practice fits their network strategy.
But these ranges are wide because specialty type, payor mix, associate physician count, and ancillary revenue streams move the number substantially. A cash-pay dermatology practice with two associate physicians and an in-house procedure suite is a fundamentally different asset than a solo Medicaid-heavy primary care practice — even if both report the same top-line revenue.
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Specialty type is the single largest driver of medical practice valuation multiples. The table below reflects 2026 private-buyer transaction ranges. PE acquisition multiples run higher across all specialties.
| Specialty | Revenue Multiple | SDE / EBITDA Multiple | PE Interest |
|---|---|---|---|
| Dermatology | 0.7x – 1.2x | 4.0x – 8.0x | Very High |
| Ophthalmology / Eye Care | 0.6x – 1.1x | 3.5x – 7.0x | High |
| Orthopedics | 0.5x – 1.0x | 3.5x – 7.0x | High |
| Gastroenterology | 0.5x – 1.0x | 3.5x – 6.5x | High |
| Pain Management | 0.5x – 1.0x | 3.0x – 6.0x | High |
| General Practice (this guide's baseline) | 0.4x – 0.8x | 2.5x – 5.0x | Moderate |
| Primary Care / Internal Medicine | 0.4x – 0.8x | 2.5x – 4.5x | Growing |
| Urgent Care | 0.4x – 0.9x | 2.5x – 5.0x | Moderate |
| OB/GYN | 0.4x – 0.8x | 2.5x – 4.5x | Moderate |
| Psychiatry / Behavioral Health | 0.4x – 0.8x | 2.5x – 4.0x | Growing |
| Medicaid-Heavy / FQHC-Style | 0.2x – 0.5x | 1.5x – 3.0x | Low |
Nothing affects medical practice value more than who pays the bills. The hierarchy, from highest to lowest value:
A practice with 40%+ Medicaid revenue will typically trade at the low end of multiples — sometimes below them. A practice with 30%+ cash-pay or out-of-network revenue will trade at the high end.
A solo physician practice is highly exposed to key-person risk. If you are the practice, buyers price that heavily. Every associate physician on staff reduces this risk and adds transferable revenue capacity. Practices with 2+ associate physicians command materially higher multiples than solo practices, all else equal.
In-house ancillary services — imaging, lab, minor surgical procedures, infusion, physical therapy, optical — generate revenue at margins far above professional services. They also represent recurring revenue tied to the facility rather than a specific physician. Ancillary revenue is often the difference between a mid-range and top-range multiple.
ACO participation, capitated managed care contracts, and PCMH designations add strategic value to primary care practices, particularly as hospital systems and PE-backed platforms look to build value-based care networks. A primary care practice with a strong quality track record in value-based care arrangements is a more attractive acquisition target than one billing purely fee-for-service.
PE-backed PMOs have been active acquirers across specialties for the past decade. Their evaluation criteria differ from a private physician buyer's in important ways:
Whether you're talking to a hospital system, a PE group, or a private buyer — walk in with a credible independent valuation.
Get My Medical Practice Valuation →Medical practice valuations use three methods, with results triangulated into a final range:
Apply the specialty-appropriate multiple to trailing 12-month collections (not billings — collections is the number that matters). For a primary care practice collecting $1.4M annually at a 0.6x multiple: $840,000 enterprise value.
Start with net income. Add back: physician owner compensation (all forms), depreciation, amortization, one-time expenses, and any personal expenses run through the practice. The result is SDE — what the practice generates for its owner. Apply the specialty multiple. For the same practice with $350,000 SDE at 3.5x: $1,225,000.
Medical equipment, leasehold improvements, supplies, and accounts receivable minus liabilities. For most practices this produces the lowest value and is used only as a floor, not a primary method.
| Item | Amount |
|---|---|
| Annual collections | $1,500,000 |
| Physician owner compensation (salary + benefits) | $280,000 |
| All other expenses | $870,000 |
| Net income | $350,000 |
| + Add back physician compensation | $280,000 |
| SDE | $630,000 |
| Revenue multiple (0.6x) | $900,000 |
| SDE multiple (3.0x) | $1,890,000 |
| Triangulated value (weighted blend) | ~$1,200,000 – $1,500,000 |
The range reflects the meaningful difference between how buyers weigh revenue vs. earnings-based methods for this practice type. A solo physician practice would land at the lower end; one with an associate MD would justify the higher end.